Validated by science
The 3 actives in NATI+ Aged Garlic (aged garlic extract, CoQ10 ubiquinol, vitamin K2 MK-7) are among the most studied supplements for the heart and blood vessels. More than 100 studies published in peer-reviewed journals. Here are the main ones, with a link to each publication.
Aged garlic, blood pressure and the arteries
Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial
Ried K. et al. · European Journal of Clinical Nutrition · 2013
Randomised trial: aged garlic extract lowers blood pressure in people with hypertension.
See the study on PubMed →Effect of garlic on blood pressure: a systematic review and meta-analysis
Ried K. et al. · BMC Cardiovascular Disorders · 2008
Meta-analysis of several trials: garlic reduces blood pressure in people with hypertension.
See the study on PubMed →Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis
Ried K. · Experimental and Therapeutic Medicine · 2020
Review and meta-analysis: lower blood pressure and more flexible arteries.
See the study on PubMed →The Effect of Kyolic Aged Garlic Extract on Gut Microbiota, Inflammation, and Cardiovascular Markers in Hypertensives: The GarGIC Trial
Ried K. et al. · Frontiers in Nutrition · 2018
GarGIC trial: effect of aged garlic on inflammation and cardiovascular markers.
See the study on PubMed →Inhibiting progression of coronary calcification using Aged Garlic Extract in patients receiving statin therapy: a preliminary study
Budoff M.J. et al. · Preventive Medicine · 2004
Aged garlic slows the progression of calcium in the arteries of the heart.
See the study on PubMed →Aged Garlic Extract Reduces Low Attenuation Plaque in Coronary Arteries of Patients with Metabolic Syndrome in a Prospective Randomized Double-Blind Study
Matsumoto S. et al. · The Journal of Nutrition · 2016
Double-blind trial: reduction of soft plaque in the coronary arteries.
See the study on PubMed →Aged garlic + CoQ10: the combination
Aged garlic extract and coenzyme Q10 have favorable effect on inflammatory markers and coronary atherosclerosis progression: A randomized clinical trial
Zeb I. et al. · Journal of Cardiovascular Disease Research · 2012
Randomised trial: the combination of aged garlic + CoQ10 acts on inflammation and atherosclerosis.
See the study on PubMed →Vitamin K2 MK-7 and artery flexibility
Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial
Knapen M.H.J. et al. · Thrombosis and Haemostasis · 2015
3-year trial at 180 µg/day: K2 MK-7 improves artery flexibility.
See the study on PubMed →CoQ10 and the heart
The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO
Mortensen S.A. et al. · JACC: Heart Failure · 2014
Double-blind Q-SYMBIO trial: CoQ10 in patients with heart failure.
See the study on PubMed →The prostate and blood vessels
Vascular damage as a risk factor for benign prostatic hyperplasia and erectile dysfunction
Berger A.P. et al. · BJU International · 2005
Damage to blood vessels is a risk factor for enlargement of the prostate and erectile problems.
See the study on PubMed →Chronic ischemia increases prostatic smooth muscle contraction in the rabbit
Azadzoi K.M. et al. · The Journal of Urology · 2003
Chronic lack of blood changes how the prostate functions.
See the study on PubMed →Structural modifications of the prostate in hypoxia, oxidative stress, and chronic ischemia
Thurmond P. et al. · Korean Journal of Urology · 2015
Review: lack of oxygen and blood changes the structure of the prostate.
See the study on PubMed →Onion and garlic intake and the odds of benign prostatic hyperplasia
Galeone C. et al. · Urology · 2007
Study: garlic and onion consumption and the risk of prostate enlargement.
See the study on PubMed →These studies cover the actives taken separately or in combination, not the finished product. This food supplement is not a substitute for medical advice or treatment. Individual results may vary.